Life as a guide to prebiotic nucleotide synthesis

Lane N, Harrison SA. Nature Commun 9: 5176 (2018). https://doi.org/10.1038/s41467-018-07220-y


Synthesis of activated nucleotides has been accomplished under ‘prebiotically plausible’ conditions, but bears little resemblance to the chemistry of life as we know it. Here we argue that life is an indispensable guide to its own origins.

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